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Year : 2013  |  Volume : 1  |  Issue : 2  |  Page : 49-56

Obesity and type 2 diabetes mellitus: A complex association

1 Department of Public Health, General Directorate of Health Affairs at Al-Ahssa Region, Ministry of Health, United Kingdom
2 Sir James Spence Institute of Child Health Institute of Health and Society, Newcastle University, United Kingdom
3 Population Health Research Centre, St. George's University of London, United Kingdom
4 Division of Public Health Institute of Psychology, Health and Society, University of Liverpool, United Kingdom

Correspondence Address:
Abdulkareem Jassem Al-Quwaidhi
P.O. Box 35515, Al-Ahssa 31982
United Kingdom
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2347-2618.128627

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Obesity is a growing epidemic affecting all ages in both industrialized and developing countries. The most common suggested cause of this epidemic is the increasing levels of urbanization and lifestyle changes toward sedentary life and adopting "western" dietary patterns. The association between obesity and type 2 diabetes mellitus (T2DM) has been reproducibly observed in cross-sectional and prospective studies across various populations, even when using different fatness measures and diagnostic criteria for T2DM. However, there are some modifying factors that make such an association complex and multifactorial. These modifying factors include the duration of obesity, body fat distribution, physical activity, diet, and genetics/ethnicity. This review aims to summarize the evidence of this association and its potential modifying factors.

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